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The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death

The Gfi-1 protooncogene encodes a nuclear zinc-finger protein that carries a novel repressor domain, SNAG, and functions as a position- and orientation-independent active transcriptional repressor. The Gfi-1 repressor allows interleukin 2 (IL-2)-dependent T cells to escape G(1) arrest induced by IL-...

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Autori principali: Grimes, H. Leighton, Gilks, C. Blake, Chan, Tung O., Porter, Susan, Tsichlis, Philip N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC26174/
https://ncbi.nlm.nih.gov/pubmed/8962093
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