The Gfi-1 protooncoprotein represses Bax expression and inhibits T-cell death

The Gfi-1 protooncogene encodes a nuclear zinc-finger protein that carries a novel repressor domain, SNAG, and functions as a position- and orientation-independent active transcriptional repressor. The Gfi-1 repressor allows interleukin 2 (IL-2)-dependent T cells to escape G(1) arrest induced by IL-...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Grimes, H. Leighton, Gilks, C. Blake, Chan, Tung O., Porter, Susan, Tsichlis, Philip N.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1996
Subjects:	Biological Sciences
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14569
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