Côd QR

Molecular ordering of the Fas-apoptotic pathway: The Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

The Fas/APO-1-receptor associated cysteine protease Mch5 (MACH/FLICE) is believed to be the enzyme responsible for activating a protease cascade after Fas-receptor ligation, leading to cell death. The Fas-apoptotic pathway is potently inhibited by the cowpox serpin CrmA, suggesting that Mch5 could b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Srinivasula, Srinivasa M., Ahmad, Manzoor, Fernandes-Alnemri, Teresa, Litwack, Gerald, Alnemri, Emad S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1996
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26159/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962078/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14486
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg