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The Lysyl Oxidase Pro-peptide Attenuates Fibronectin-mediated Activation of Focal Adhesion Kinase and p130(Cas) in Breast Cancer Cells

The lysyl oxidase (LOX) gene encodes an enzyme (LOX) critical for extracellular matrix maturation. The LOX gene has also been shown to inhibit the transforming activity of Ras oncogene signaling. In particular, the pro-peptide domain (LOX-PP) released from the secreted precursor protein (Pro-LOX) wa...

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Библиографические подробности
Главные авторы: Zhao, Yingshe, Min, Chengyin, Vora, Siddharth R., Trackman, Philip C., Sonenshein, Gail E., Kirsch, Kathrin H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615524/
https://ncbi.nlm.nih.gov/pubmed/19029090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802612200
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