Membrane-type 1 Matrix Metalloproteinase Regulates Macrophage-dependent Elastolytic Activity and Aneurysm Formation in Vivo

During arterial aneurysm formation, levels of the membrane-anchored matrix metalloproteinase, MT1-MMP, are elevated dramatically. Although MT1-MMP is expressed predominately by infiltrating macrophages, the roles played by the proteinase in abdominal aortic aneurysm (AAA) formation in vivo remain un...

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Bibliografske podrobnosti
Main Authors: Xiong, Wanfen, Knispel, Rebecca, MacTaggart, Jason, Greiner, Timothy C., Weiss, Stephen J., Baxter, B. Timothy
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Glycobiology and Extracellular Matrices
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615502/
https://ncbi.nlm.nih.gov/pubmed/19010778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806239200
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