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Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

Matrix metalloproteinases (MMPs) 9 and 2 are increased in human abdominal aortic aneurysm (AAA) tissue, but their precise role and potential interaction remain unclear. Experimental induction of aortic aneurysms in mice genetically deficient in these peptidases could provide new insight into AAA pat...

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Detalles Bibliográficos
Main Authors: Longo, G. Matthew, Xiong, Wanfen, Greiner, Timothy C., Zhao, Yong, Fiotti, Nicola, Baxter, B. Timothy
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC151106/
https://ncbi.nlm.nih.gov/pubmed/12208863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15334
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