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Anti-Aß immunotherapy in Alzheimer's disease; relevance of transgenic mouse studies to clinical trials

Therapeutic approaches to the treatment of Alzheimer's disease are focused primarily on the Aß peptide which aggregates to form amyloid deposits in the brain. The amyloid hypothesis states that amyloid is the precipitating factor that results in the other pathologies of Alzheimer's, namely...

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Autors principals: Wilcock, Donna M., Colton, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615484/
https://ncbi.nlm.nih.gov/pubmed/19096156
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