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Anti-Aß immunotherapy in Alzheimer's disease; relevance of transgenic mouse studies to clinical trials

Therapeutic approaches to the treatment of Alzheimer's disease are focused primarily on the Aß peptide which aggregates to form amyloid deposits in the brain. The amyloid hypothesis states that amyloid is the precipitating factor that results in the other pathologies of Alzheimer's, namely...

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Autori principali: Wilcock, Donna M., Colton, Carol A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615484/
https://ncbi.nlm.nih.gov/pubmed/19096156
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