CAVEOLAE ARE AN ESSENTIAL COMPONENT OF THE PATHWAY FOR ENDOTHELIAL CELL SIGNALING ASSOCIATED WITH ABRUPT REDUCTION OF SHEAR STRESS

Abrupt cessation of flow representing the acute loss of shear stress (simulated ischemia) to flow-adapted pulmonary microvascular endothelial cells (PMVEC) leads to reactive oxygen species (ROS) generation that signals for EC proliferation. We evaluated the role of caveolin-1 on this cellular respon...

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Detalhes bibliográficos
Main Authors: Milovanova, Tatyana, Chatterjee, Shampa, Hawkins, Brian J., Hong, NanKang, Sorokina, Elena M., DeBolt, Kris, Moore, Jonni S., Madesh, Muniswamy, Fisher, Aron B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615406/
https://ncbi.nlm.nih.gov/pubmed/18573285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.05.010
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