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Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
Stem cells persist throughout life by self-renewing in numerous tissues including the central1 and peripheral2 nervous systems. This raises the issue of whether there is a conserved mechanism to effect self-renewing divisions. Deficiency in the polycomb family transcriptional repressor Bmi-1 leads t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614897/ https://ncbi.nlm.nih.gov/pubmed/14574365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature02060 |
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