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Conditional Activation of a Single-Copy L1 Transgene in Mice by Cre

The synthetic L1 retrotransposon, ORFeus, is useful for probing mechanisms of L1 retrotransposition in vivo and for genome-wide mouse mutagenesis because of its high level of activity. To achieve controlled activation of ORFeus in mice, we constructed ORFeus(LSL), in which ORFeus coding sequences we...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: An, Wenfeng, Han, Jeffrey S., Schrum, Christina M., Maitra, Anirban, Koentgen, Frank, Boeke, Jef D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614868/
https://ncbi.nlm.nih.gov/pubmed/18615728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20407
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