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Active retrotransposition by a synthetic L1 element in mice

Long interspersed element type 1 (L1) retrotransposons are ubiquitous mammalian mobile elements and potential tools for in vivo mutagenesis; however, native L1 elements are relatively inactive in mice when introduced as transgenes. We have previously described a synthetic L1 element, ORFeus, contain...

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Detalhes bibliográficos
Main Authors: An, Wenfeng, Han, Jeffrey S., Wheelan, Sarah J., Davis, Edward S., Coombes, Candice E., Ye, Ping, Triplett, Christina, Boeke, Jef D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693719/
https://ncbi.nlm.nih.gov/pubmed/17124176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605300103
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