Φορτώνει......
Pruning and loss of excitatory synapses by the parkin ubiquitin ligase
Mutations in the PARK2 gene cause hereditary Parkinson disease (PD). The PARK2 gene product, termed parkin, is an E3 ubiquitin ligase that mediates the transfer of ubiquitin onto diverse substrate proteins. Despite progress in defining the molecular properties and substrates of parkin, little is kno...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614788/ https://ncbi.nlm.nih.gov/pubmed/19033459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802280105 |
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