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Inhibition of cyclooxygenase activity blocks cell-to-cell spread of human cytomegalovirus

Human cytomegalovirus has previously been shown to induce the accumulation of cyclooxygenase-2 RNA, protein, and enzyme activity. High doses of cyclooxygenase inhibitors substantially block viral replication in cultured fibroblasts. However, doses corresponding to the level of drug achieved in the p...

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Hlavní autoři: Schröer, Jörg, Shenk, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614784/
https://ncbi.nlm.nih.gov/pubmed/19033472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810740105
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