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Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway

Substrates of the N-end rule pathway include proteins with destabilizing N-terminal residues. These residues are recognized by E3 ubiquitin ligases called N-recognins. Ubr1 is the N-recognin of the yeast Saccharomyces cerevisiae. Extracellular amino acids or short peptides up-regulate the peptide tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hwang, Cheol-Sang, Varshavsky, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614737/
https://ncbi.nlm.nih.gov/pubmed/19033468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808891105
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