HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

The overlapping histological and biochemical features underlying the beneficial effect of deacetylase inhibitors and NO donors in dystrophic muscles suggest an unanticipated molecular link among dystrophin, NO signaling, and the histone deacetylases (HDACs). Higher global deacetylase activity and se...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Colussi, Claudia, Mozzetta, Chiara, Gurtner, Aymone, Illi, Barbara, Rosati, Jessica, Straino, Stefania, Ragone, Gianluca, Pescatori, Mario, Zaccagnini, Germana, Antonini, Annalisa, Minetti, Giulia, Martelli, Fabio, Piaggio, Giulia, Gallinari, Paola, Steinkuhler, Christian, Clementi, Emilio, Dell'Aversana, Carmela, Altucci, Lucia, Mai, Antonello, Capogrossi, Maurizio C., Puri, Pier Lorenzo, Gaetano, Carlo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2008
Θέματα:
Biological Sciences
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614736/
https://ncbi.nlm.nih.gov/pubmed/19047631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805514105
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