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Equilibrium constants and free energies in unfolding of proteins in urea solutions

A novel thermodynamic approach to the reversible unfolding of proteins in aqueous urea solutions has been developed based on the premise that urea ligands are bound cooperatively to the macromolecule. When successive stoichiometric binding constants have values larger than expected from statistical...

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Autor principal: Klotz, Irving M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC26146/
https://ncbi.nlm.nih.gov/pubmed/8962065
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