Timing of adenosine 2A receptor stimulation relative to reperfusion has differential effects on infarct size and cardiac function as assessed in mice by MRI

The activation of adenosine 2A receptors before reperfusion following coronary artery occlusion reduces infarct size and improves ejection fraction (EF). In this study, we examined the effects of delaying treatment with the adenosine 2A receptor agonist ATL146e (ATL) until 1 h postreperfusion. The i...

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Hauptverfasser: Yang, Zequan, Linden, Joel, Berr, Stuart S., Kron, Irving L., Beller, George A., French, Brent A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2008
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614530/
https://ncbi.nlm.nih.gov/pubmed/18849340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00091.2008
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