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Acute hyperglycemia enhances oxidative stress and exacerbates myocardial infarction by activating NADPH oxidase during reperfusion

OBJECTIVE: Acute hyperglycemia is independently associated with larger myocardial infarct size (IF) in both diabetic and non-diabetic patients. We hypothesized that the oxidative stress imposed by acute hyperglycemia contributes to the exacerbation of IF during reperfusion. METHODS: C57BL/6 mice und...

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Bibliografische gegevens
Hoofdauteurs: Yang, Zequan, Laubach, Victor E., French, Brent A., Kron, Irving L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680027/
https://ncbi.nlm.nih.gov/pubmed/19258097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2008.08.056
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