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Acute hyperglycemia enhances oxidative stress and exacerbates myocardial infarction by activating NADPH oxidase during reperfusion
OBJECTIVE: Acute hyperglycemia is independently associated with larger myocardial infarct size (IF) in both diabetic and non-diabetic patients. We hypothesized that the oxidative stress imposed by acute hyperglycemia contributes to the exacerbation of IF during reperfusion. METHODS: C57BL/6 mice und...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680027/ https://ncbi.nlm.nih.gov/pubmed/19258097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2008.08.056 |
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