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Atorvastatin at Reperfusion Reduces Myocardial Infarct Size in Mice by Activating eNOS in Bone Marrow-Derived Cells

BACKGROUND: The current study was designed to test our hypothesis that atorvastatin could reduce infarct size in intact mice by activating eNOS, specifically the eNOS in bone marrow-derived cells. C57BL/6J mice (B6) and congenic eNOS knockout (KO) mice underwent 45 min LAD occlusion and 60 min reper...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tian, Yikui, Linden, Joel, French, Brent A., Yang, Zequan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254980/
https://ncbi.nlm.nih.gov/pubmed/25470018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114375
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