Targeting aspartate aminotransferase in breast cancer

INTRODUCTION: Glycolysis is increased in breast adenocarcinoma cells relative to adjacent normal cells in order to produce the ATP and anabolic precursors required for survival, growth and invasion. Glycolysis also serves as a key source of the reduced form of cytoplasmic nicotinamide adenine dinucl...

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Detalhes bibliográficos
Main Authors: Thornburg, Joshua Marshall, Nelson, Kristin K, Clem, Brian F, Lane, Andrew N, Arumugam, Sengodagounder, Simmons, Allan, Eaton, John W, Telang, Sucheta, Chesney, Jason
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614520/
https://ncbi.nlm.nih.gov/pubmed/18922152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2154
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