Cytochrome c oxidase is activated by the oncoprotein Ras and is required for A549 lung adenocarcinoma growth

BACKGROUND: Constitutive activation of Ras in immortalized bronchial epithelial cells increases electron transport chain activity, oxygen consumption and tricarboxylic acid cycling through unknown mechanisms. We hypothesized that members of the Ras family may stimulate respiration by enhancing the e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Telang, Sucheta, Nelson, Kristin K, Siow, Deanna L, Yalcin, Abdullah, Thornburg, Joshua M, Imbert-Fernandez, Yoannis, Klarer, Alden C, Farghaly, Hanan, Clem, Brian F, Eaton, John W, Chesney, Jason
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546037/
https://ncbi.nlm.nih.gov/pubmed/22917272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-60
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