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Differential Effects of JNK1 and JNK2 Inhibition on Murine Steatohepatitis and Insulin Resistance

Activation of c-Jun N-terminal kinase (JNK) has been implicated as a mechanism in the development of steatohepatitis. This finding together with the reported role of JNK signaling in the development of obesity and insulin resistance, two components of the metabolic syndrome and predisposing factors...

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Detalhes bibliográficos
Main Authors: Singh, Rajat, Wang, Yongjun, Xiang, Youqing, Tanaka, Kathryn E., Gaarde, William A., Czaja, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614457/
https://ncbi.nlm.nih.gov/pubmed/19053047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22578
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