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Pharmacologic and Genetic Manipulation of Matrix Metalloproteinases -2 and -9 Reduce Retinal Neovascularization in Rodent Models of Retinopathy of Prematurity
PURPOSE: In order to examine the roles of MMP-2 and MMP-9 in retinal neovascularization, the efficacy of three matrix metalloproteinase (MMP) inhibitors with varying selectivity, (Ro-31-9790, AG3340 and DPC-A37668) was investigated in a rat model of retinopathy of prematurity. The susceptibilities o...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614400/ https://ncbi.nlm.nih.gov/pubmed/17251494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.06-0082 |
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