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VISUALIZATION OF THE HYBRID STATE OF tRNA BINDING PROMOTED BY SPONTANEOUS RATCHETING OF THE RIBOSOME

A crucial step in protein translation is the translocation of tRNAs through the ribosome. In the transition from one canonical site to the other, the tRNAs acquire intermediate configurations, so-called hybrid states. At this stage, the small subunits is rotated with respect to the large subunit, an...

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Detalhes bibliográficos
Main Authors: Agirrezabala, Xabier, Lei, Jianlin, Brunelle, Julie L., Ortiz-Meoz, Rodrigo F., Green, Rachel, Frank, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614368/
https://ncbi.nlm.nih.gov/pubmed/18951087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.10.001
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