Recognition of aminoacyl-tRNA: a common molecular mechanism revealed by cryo-EM

The accuracy of ribosomal translation is achieved by an initial selection and a proofreading step, mediated by EF-Tu, which forms a ternary complex with aminoacyl(aa)-tRNA. To study the binding modes of different aa-tRNAs, we compared cryo-EM maps of the kirromycin-stalled ribosome bound with ternar...

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Main Authors: Li, Wen, Agirrezabala, Xabier, Lei, Jianlin, Bouakaz, Lamine, Brunelle, Julie L, Ortiz-Meoz, Rodrigo F, Green, Rachel, Sanyal, Suparna, Ehrenberg, Måns, Frank, Joachim
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586802/
https://ncbi.nlm.nih.gov/pubmed/19020518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.243
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