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Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate

Ceramidases catalyze hydrolysis of ceramides to generate sphingosine (SPH), which is phosphorylated to form sphingosine-1-phosphate (S1P). Ceramide, SPH, and S1P are bioactive lipids that mediate cell proliferation, differentiation, apoptosis, adhesion, and migration, likely by controlling hydrolysi...

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Detalhes bibliográficos
Main Authors: Mao, Cungui, Obeid, Lina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614331/
https://ncbi.nlm.nih.gov/pubmed/18619555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2008.06.002
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