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Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate
Ceramidases catalyze hydrolysis of ceramides to generate sphingosine (SPH), which is phosphorylated to form sphingosine-1-phosphate (S1P). Ceramide, SPH, and S1P are bioactive lipids that mediate cell proliferation, differentiation, apoptosis, adhesion, and migration, likely by controlling hydrolysi...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614331/ https://ncbi.nlm.nih.gov/pubmed/18619555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2008.06.002 |
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