HIGH-RESOLUTION GENOMIC ARRAYS FACILITATE DETECTION OF NOVEL CRYPTIC CHROMOSOMAL LESIONS IN MYELODYSPLASTIC SYNDROMES

OBJECTIVE: Unbalanced chromosomal aberrations are common in myelodysplastic syndromes, and have prognostic implications. An increased frequency of cytogenetic changes may reflect an inherent chromosomal instability due to failure of DNA repair. Therefore, it is likely that chromosomal defects in mye...

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Huvudupphovsmän: O’Keefe, Christine L., Tiu, Ramon, Gondek, Lukasz P., Powers, Jennifer, Theil, Karl S., Kalaycio, Matt, Lichtin, Alan, Sekeres, Mikkael A., Maciejewski, Jaroslaw P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613764/
https://ncbi.nlm.nih.gov/pubmed/17258073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2006.09.016
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