New Lesions Detected by Single Nucleotide Polymorphism Array–Based Chromosomal Analysis Have Important Clinical Impact in Acute Myeloid Leukemia

PURPOSE: Cytogenetics is the primary outcome predictor in acute myeloid leukemia (AML). Metaphase cytogenetics (MC) detects an abnormal karyotype in only half of patients with AML, however. Single nucleotide polymorphism arrays (SNP-A) can detect acquired somatic uniparental disomy (UPD) and other c...

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Hauptverfasser: Tiu, Ramon V., Gondek, Lukasz P., O'Keefe, Christine L., Huh, Jungwon, Sekeres, Mikkael A., Elson, Paul, McDevitt, Michael A., Wang, Xiao Fei, Levis, Mark J., Karp, Judith E., Advani, Anjali S., Maciejewski, Jaroslaw P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2009
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Original Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773477/
https://ncbi.nlm.nih.gov/pubmed/19770377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.21.9840
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