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Phosphatidylinositol 3-Kinase Pathway Regulates Hypoxia-Inducible Factor-1 to Protect from Intestinal Injury during Necrotizing Enterocolitis
BACKGROUND: Hypoxia is an important risk factor for development of necrotizing enterocolitis (NEC) in premature infants. Hypoxia-inducible factor (HIF)-1 is a transcription factor that plays a critical role in cellular responses to hypoxia and can be induced by phosphatidylinositol 3-kinase (PI3-K)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613757/ https://ncbi.nlm.nih.gov/pubmed/17689699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2007.04.018 |
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