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Conserved central domains control the quaternary structure of Type I and Type II Hsp40 molecular chaperones

Hsp40s play an essential role in protein metabolism by regulating the polypeptide binding and release cycle of Hsp70. The Hsp40 family is large and specialized family members direct Hsp70 to perform highly specific tasks. Type I and Type II Hsp40s, such as yeast Ydj1 and Sis1, are homodimers that di...

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Autors principals: Ramos, Carlos H.I., Oliveira, Cristiano L.P., Yang-Fan, Chung, Torriani, Iris L., Cyr, Douglas M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613655/
https://ncbi.nlm.nih.gov/pubmed/18723025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.08.019
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