Regulation of Chemerin Bioactivity by Plasma Carboxypeptidase N, Carboxypeptidase B (Activated Thrombin-activable Fibrinolysis Inhibitor), and Platelets

Chemerin is a potent chemoattractant for cells expressing the serpentine receptor CMKLR1 (chemokine-like receptor 1), such as plasmacytoid dendritic cells and tissue macrophages. The bioactivity of chemerin is post-translationally regulated; the attractant circulates in blood in a relatively inactiv...

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Bibliographische Detailangaben
Hauptverfasser: Du, Xiao-Yan, Zabel, Brian A., Myles, Timothy, Allen, Samantha J., Handel, Tracy M., Lee, Peter P., Butcher, Eugene C., Leung, Lawrence L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Enzyme Catalysis and Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613638/
https://ncbi.nlm.nih.gov/pubmed/19010784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805000200
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