PEG Minocycline-Liposomes Ameliorate CNS Autoimmune Disease

BACKGROUND: Minocycline is an oral tetracycline derivative with good bioavailability in the central nervous system (CNS). Minocycline, a potent inhibitor of matrix metalloproteinase (MMP)-9, attenuates disease activity in experimental autoimmune encephalomyelitis (EAE), an animal model of multiple s...

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Main Authors: Hu, Wei, Metselaar, Josbert, Ben, Li-Hong, Cravens, Petra D., Singh, Mahendra P., Frohman, Elliot M., Eagar, Todd N., Racke, Michael K., Kieseier, Bernd C., Stüve, Olaf
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613526/
https://ncbi.nlm.nih.gov/pubmed/19127301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004151
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