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Accumulation of Phosphorylated β-Catenin Enhances ROS-Induced Cell Death in Presenilin-Deficient Cells

Presenilin (PS) is involved in many cellular events under physiological and pathological conditions. Previous reports have revealed that PS deficiency results in hyperproliferation and resistance to apoptotic cell death. In the present study, we investigated the effects of PS on β-catenin and cell m...

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Detalles Bibliográficos
Main Authors: Boo, Jung H., Song, Hyundong, Kim, Ji E., Kang, David E., Mook-Jung, Inhee
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613523/
https://ncbi.nlm.nih.gov/pubmed/19137062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004172
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