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Extracellular Matrix Regulation of Autophagy

Integrin-mediated attachment of epithelial cells to extracellular matrix (ECM) is critical for proper growth and survival. Although detachment leads to apoptosis, termed anoikis, recent work demonstrates that ECM detachment also robustly induces autophagy, a tightly regulated lysosomal self-digestio...

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Detalhes bibliográficos
Main Authors: Lock, Rebecca, Debnath, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613490/
https://ncbi.nlm.nih.gov/pubmed/18573652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.05.002
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