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Extracellular Matrix Regulation of Autophagy
Integrin-mediated attachment of epithelial cells to extracellular matrix (ECM) is critical for proper growth and survival. Although detachment leads to apoptosis, termed anoikis, recent work demonstrates that ECM detachment also robustly induces autophagy, a tightly regulated lysosomal self-digestio...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613490/ https://ncbi.nlm.nih.gov/pubmed/18573652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.05.002 |
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