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Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

Autophagy has been proposed to promote cell death during lumen formation in three-dimensional mammary epithelial acini because numerous autophagic vacuoles are observed in the dying central cells during morphogenesis. Because these central cells die due to extracellular matrix (ECM) deprivation (ano...

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Detalhes bibliográficos
Main Authors: Fung, Christopher, Lock, Rebecca, Gao, Sizhen, Salas, Eduardo, Debnath, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2262959/
https://ncbi.nlm.nih.gov/pubmed/18094039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1092
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