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Extracellular Matrix Regulation of Autophagy

Integrin-mediated attachment of epithelial cells to extracellular matrix (ECM) is critical for proper growth and survival. Although detachment leads to apoptosis, termed anoikis, recent work demonstrates that ECM detachment also robustly induces autophagy, a tightly regulated lysosomal self-digestio...

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Dettagli Bibliografici
Autori principali: Lock, Rebecca, Debnath, Jayanta
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613490/
https://ncbi.nlm.nih.gov/pubmed/18573652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2008.05.002
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