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IL-17A and IL-17F do not contribute vitally to autoimmune neuro-inflammation in mice

The clear association of Th17 cells with autoimmune pathogenicity implicates Th17 cytokines as critical mediators of chronic autoimmune diseases such as EAE. To study the impact of IL-17A on CNS inflammation, we generated transgenic mice in which high levels of expression of IL-17A could be initiate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Haak, Stefan, Croxford, Andrew L., Kreymborg, Katharina, Heppner, Frank L., Pouly, Sandrine, Becher, Burkhard, Waisman, Ari
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613466/
https://ncbi.nlm.nih.gov/pubmed/19075395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35997
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