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Direct imaging of human Rad51 nucleoprotein dynamics on individual DNA molecules

Rad51 protein (Rad51) is central to recombinational repair of double-strand DNA breaks. It polymerizes onto DNA and promotes strand exchange between homologous chromosomes. We visualized the real-time assembly and disassembly of human Rad51 nucleoprotein filaments on double-stranded DNA by single-mo...

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Hlavní autoři: Hilario, Jovencio, Amitani, Ichiro, Baskin, Ronald J., Kowalczykowski, Stephen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613362/
https://ncbi.nlm.nih.gov/pubmed/19122145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811965106
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