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Single-Molecule Imaging Brings Rad51 Nucleoprotein Filaments into Focus
The Rad51 protein is essential for DNA repair by homologous recombination. Following DNA damage, Rad51 localizes into nuclear foci that represent sites of DNA repair in vivo. In vitro, Rad51 self-assembles on single- or double-stranded DNA to form a nucleoprotein filament. Recently, the merging of i...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862779/ https://ncbi.nlm.nih.gov/pubmed/20299221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2010.02.004 |
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