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VEGF-A splicing: the key to anti-angiogenic therapeutics?

The physiology of microvessels limits the growth and development of tumours. Tumours gain nutrients and excrete waste through growth-associated microvessels. New anticancer therapies target this microvasculature by inhibiting vascular endothelial growth factor A (VEGF-A) splice isoforms that promote...

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Bibliographic Details
Main Authors: Harper, Steven J., Bates, David O.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613352/
https://ncbi.nlm.nih.gov/pubmed/18923433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2505
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