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SHARP1/DEC2 inhibits adipogenic differentiation by regulating the activity of C/EBP

SHARP1, a basic helix–loop–helix transcription factor, is expressed in many cell types; however, the mechanisms by which it regulates cellular differentiation remain largely unknown. Here, we show that SHARP1 negatively regulates adipogenesis. Although expression of the early marker CCAAT/enhancer b...

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Main Authors: Gulbagci, Neriman Tuba, Li, Li, Ling, Belinda, Gopinadhan, Suma, Walsh, Martin, Rossner, Moritz, Nave, Klaus-Armin, Taneja, Reshma
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613201/
https://ncbi.nlm.nih.gov/pubmed/19029947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.207
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