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G9a mediates Sharp-1–dependent inhibition of skeletal muscle differentiation

Sharp-1, a basic helix-loop-helix transcription factor, is a potent repressor of skeletal muscle differentiation and is dysregulated in muscle pathologies. However, the mechanisms by which it inhibits myogenesis are not fully understood. Here we show that G9a, a lysine methyltransferase, is involved...

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Detalhes bibliográficos
Main Authors: Ling, Belinda Mei Tze, Gopinadhan, Suma, Kok, Wai Kay, Shankar, Shilpa Rani, Gopal, Pooja, Bharathy, Narendra, Wang, Yaju, Taneja, Reshma
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521685/
https://ncbi.nlm.nih.gov/pubmed/23087213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-04-0311
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