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Localization of Double-stranded Small Interfering RNA to Cytoplasmic Processing Bodies Is Ago2 Dependent and Results in Up-Regulation of GW182 and Argonaute-2
Processing bodies (P-bodies) are cytoplasmic foci implicated in the regulation of mRNA translation, storage, and degradation. Key effectors of microRNA (miRNA)-mediated RNA interference (RNAi), such as Argonaute-2 (Ago2), miRNAs, and their cognate mRNAs, are localized to these structures; however, t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613116/ https://ncbi.nlm.nih.gov/pubmed/18946079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-08-0796 |
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