Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a major cause of loss of central vision in the elderly. The formation of drusen, an extracellular, amorphous deposit of material on Bruch's membrane in the macula of the retina, occurs early in the course of the disease. Although some of the molecular c...

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Bibliografiske detaljer
Main Authors: Wang, Ai Ling, Lukas, Thomas J., Yuan, Ming, Du, Nga, Tso, Mark O., Neufeld, Arthur H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612751/
https://ncbi.nlm.nih.gov/pubmed/19129916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004160
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