Autophagy and Exosomes in the Aged Retinal Pigment Epithelium: Possible Relevance to Drusen Formation and Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a major cause of loss of central vision in the elderly. The formation of drusen, an extracellular, amorphous deposit of material on Bruch's membrane in the macula of the retina, occurs early in the course of the disease. Although some of the molecular c...

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Hlavní autoři: Wang, Ai Ling, Lukas, Thomas J., Yuan, Ming, Du, Nga, Tso, Mark O., Neufeld, Arthur H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612751/
https://ncbi.nlm.nih.gov/pubmed/19129916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004160
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