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p53 Chromatin Epigenetic Domain Organization and p53 Transcription

Epigenetic organization represents an important regulation mechanism of gene expression. In this work, we show that the mouse p53 gene is organized into two epigenetic domains. The first domain is fully unmethylated, associated with histone modifications in active genes, and organized in a nucleosom...

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Bibliographic Details
Main Authors: Su, Chia-Hsin, Shann, Yih-Jyh, Hsu, Ming-Ta
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612499/
https://ncbi.nlm.nih.gov/pubmed/18936172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00704-08
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