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Insertional Gene Activation by Lentiviral and Gammaretroviral Vectors
Gammaretroviral and lentiviral vectors are promising tools for gene therapy, but they can be oncogenic. The development of safer vectors depends on a quantitative assay for insertional mutagenesis. Here we report a rapid, inexpensive, and reproducible assay which uses a murine cell line to measure t...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612344/ https://ncbi.nlm.nih.gov/pubmed/18945765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01865-08 |
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