HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1

Human immunodeficiency virus type 1 (HIV-1)-infected persons who maintain plasma viral loads of <50 copies RNA/ml without treatment have been termed elite controllers (EC). Factors contributing to durable control of HIV in EC are unknown, but an HLA-dependent mechanism is suggested by overreprese...

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Autors principals: Miura, Toshiyuki, Brockman, Mark A., Brumme, Zabrina L., Brumme, Chanson J., Pereyra, Florencia, Trocha, Alicja, Block, Brian L., Schneidewind, Arne, Allen, Todd M., Heckerman, David, Walker, Bruce D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612337/
https://ncbi.nlm.nih.gov/pubmed/18971283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01471-08
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